Design, Evaluation, and Dissemination of a Plastic Syringe Clip to Improve Dosing Accuracy of Liquid Medications
- Design, Evaluation, and Dissemination of a Plastic Syringe Clip to Improve Dosing Accuracy of Liquid Medications.
- Annals of Biomedical Engineering, pp. 1––9, 2013.
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Pediatricians in Africa requested a tool to improve caregiver dosing of liquid antiretroviral medication. We developed, evaluated and disseminated a clip to control the amount of medication drawn into an oral syringe. In a laboratory, a user tested clips of different lengths, corre- sponding to different volumes, by drawing water into a syringe with a clip. In Texas and Malawi, 149 adults attempted to measure Pepto-BismolTM using a syringe with a clip, a syringe without a clip, and a dosing cup, in a randomly assigned order. In the laboratory, the volume of liquid, ranging from 1 to 4.5 mL, drawn into the syringe was always within at least 5 lL of the intended dose. In Texas, 84% of doses were accurate within $\pm$10%, vs. 63% using the syringe alone, and 21% with the dosing cup. In Malawi, 98% of doses were accurate to within $\pm$10%, vs. 90% using the syringe alone, and 27% with the dosing cup. For target accuracy values within $\pm$45% ($\pm$21%), a significantly higher fraction of Houston (Kamangira) participants delivered an accurate dose using the syringe with the clip than with the syringe alone (p<0.05). The clip enables a greater propor- tion of users to accurately measure liquid medication.
@Article{syringe,
author = {Garrett J Spiegel and Cindy Dinh and Amanda Gutierrez and Julia Lukomnik and Benjamin Lu and Kamal Shah and Tara Slough and Ping Teresa Yeh and Yvette Mirabal and Lauren Vestewig Gray and {others}},
journal = {Annals of Biomedical Engineering},
pages = {1––9},
title = {Design, Evaluation, and Dissemination of a Plastic Syringe Clip to Improve Dosing Accuracy of Liquid Medications},
year = {2013},
}